The medication is sent to your pharmacy. It usually costs about less than 20 dollars.
We advice you to use GoodRx coupons by visiting their site (https://www.goodrx.com/) for discounts.

Patients in the randomized controlled trials lost between 9% – 12%
My patients along with the dietary advice lose close to 15% – 20%. For someone who weighs close to 200 lbs, I expect them to lose 30 lbs

The randomized controlled trials were done with both medications take together. In my practice we have seen a better response when the medication is taken together.
As we know Phentermine can lead to jitteriness, high energy state and topamax balances this side effect out. Hence the combination works really well.

The total cost is usually less than $30 if you pay cash and use goodrx coupons.

If you have BMI > 30, or BMI > 27 with hypertension, diabetes or obstructive sleep apnea, and do not have any contraindications
BMI Calculator Link https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm

It is classified as a sympathomimetic amine and functions as an appetite suppressant.
Here’s how phentermine works:
1. Appetite Suppression: Phentermine stimulates the release of certain chemicals in the brain, such as norepinephrine, which activates the “fight or flight” response. This activation leads to a decrease in appetite and an increased feeling of fullness. By reducing hunger and cravings, phentermine helps individuals consume fewer calories and supports weight loss efforts.
2. Increased Energy Expenditure: Phentermine also stimulates the release of adrenaline, which can increase energy expenditure and metabolic rate. This effect may contribute to weight loss by burning more calories.
3. Central Nervous System Stimulation: Phentermine acts on the central nervous system, specifically the hypothalamus, to reduce hunger signals and increase satiety. It affects certain neurotransmitters, such as dopamine and serotonin, which are involved in regulating appetite and mood.

It’s important to note that phentermine is typically prescribed for short-term use, usually a few weeks to a few months, due to concerns about potential side effects and the risk of developing tolerance to its effects

It is FDA approved medication but can have side effects.
Common side effects of Phentermine can include:
1. Increased Heart Rate: Phentermine is a stimulant, and one of its effects is an increase in heart rate. Some people may experience a faster or irregular heartbeat while taking phentermine.
2. Elevated Blood Pressure: Phentermine can raise blood pressure levels, and individuals with pre-existing hypertension should be cautious when using this medication. Regular monitoring of blood pressure is recommended during treatment.
3. Insomnia: Phentermine is known to have stimulating effects on the central nervous system, which can lead to difficulty falling asleep or staying asleep. Taking phentermine too late in the day may exacerbate insomnia.
4. Dry Mouth: Phentermine can cause a reduction in saliva production, leading to a dry or uncomfortable sensation in the mouth. Staying hydrated and chewing sugar-free gum may help alleviate this side effect.
5. Gastrointestinal Issues: Some individuals may experience digestive disturbances such as constipation, diarrhea, or stomach discomfort while taking phentermine.
6. Restlessness or Nervousness: Phentermine’s stimulating effects can sometimes lead to feelings of restlessness, nervousness, or anxiety in some individuals.
7. Dizziness or Headache: These symptoms may occur as a result of changes in blood pressure or the stimulant effects of phentermine.
It’s important to remember that not everyone will experience these side effects, and the severity and frequency can vary among individuals. If experience any bothersome or persistent side effects, it’s recommended to stop the medication and contact us immediately.

After initial treatment with Phentermine/Topamax for few months the patient is swithced over to Semaglutide.
This approach helps patients to maximise weight loss by working different mechanism of actions of medications.